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Jarrow Formulas SAM-e 200 provides a full 200 mg SAM-e (net yield) from 400 mg of SAM-e tosylate disulfate. SAM-e 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product. Contains More of the Active S,S Form Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S,S) SAM-e, the highest active level available. SAM-e has been clinically shown to have the following benefits: Joint Strength SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM-e metabolites. Brain Metabolism SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin). Liver SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are substances important for liver function. Warnings: Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using. Individuals with Parkinson’s disease, bi-polar disorder or manic depression should not use SAM-e. Do not use if pregnant or nursing. Do not exceed recommended dose. May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use. Keep out of the reach of children. Additional Info: Jarrow Formulas SAM-e 200 is foil blister-packed to maximize stability and safety. DO NOT use if outer seal of blister pack is broken. Store in a cool, dry place. Suitable for vegetarians/vegans. Packaging: Paperboard/Blister Pack Other Ingredients: Cellulose, Mannitol, Glyceryl Behenate, Magnesium Stearate (Vegetable Source), Silicon Dioxide, Sodium Starch Glycolate, Enteric Coating (Methacrylate Copolymers), Magnesium Silicate, Titanium Dioxide, Triethyl citrate, and Riboflavin. Does Not Contain: Wheat, Gluten, Soybeans, Dairy, Egg, Fish/Shellfish, Peanuts/Tree Nuts. Suggested Use: Take 1 tablet 1 or 2 times per day on an empty stomach or as directed by your qualified healthcare professional.
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